Date of Award
2010
Document Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
Department
Biology
Abstract
The extracellular matrix (ECM) is an essential requirement for maintaining permanent shape and rigidity in multicellular organisms. The ECM serves two main functions: scaffolding and signaling. Insoluble collagen and soluble proteoglycans, glycosaminoglycans (GAGs), and glycoproteins allow for water retention and flexibility. The signaling role of the ECM is essential for a multitude of events including vascular development and angiogenesis. Via interactions with vascular endothelial cells, proteins of the ECM can induce or repress angiogenesis.
Recommended Citation
Williams, Kent Edward, "Extracellular Matrix Proteins: Implications For Angiogenesis" (2010). All-Inclusive List of Electronic Theses and Dissertations. 1945.
https://scholars.indianastate.edu/etds/1945